The Effect of Lipid Shortages and the Development of EFA Deficiency in Inpatient and Outpatients on Parenteral Nutrition
Patricia Brown*, RD, LDN, CNSC, Carol Tiffany‡, MS
*Parenteral and Enteral Support Service of The Johns Hopkins Hospital, Baltimore, Maryland, ‡Kennedy Krieger Institute Peroxisomal Diseases Lab, Baltimore, MD
The Effect of Lipid Shortages and the Development of EFA Deficiency in Inpatient and Outpatients on Parenteral Nutrition
Patricia Brown*, RD, LDN, CNSC, Carol Tiffany‡, MS
*Parenteral and Enteral Support Service of The Johns Hopkins Hospital, Baltimore, Maryland, ‡Kennedy Krieger Institute Peroxisomal Diseases Lab, Baltimore, MD
Important Findings: We performed baseline RBC EFA panels on all PN patients which were all initially negative, indicating that the EFA Plasma deficiency developed short term. All Inpatients became EFA deficient as early as day 10. The minimum lipid recommendations were not enough to improve the EFA deficiency. None of the outpatients became EFA deficient even by day 26 of lipid free PN. The Inpatient who was advanced to a fat containing diet showed a more pronounced EFA deficiency on recheck.The difference in plasma EFA levels between inpatients and outpatients suggests that inflammation or malnutrition may play a role in the acceleration of lipid deficiency.
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